The original call
Original year: 2012
2026 assessment
Scorecard verdict: Nailed it
Nailed it. The cost curve was real and it kept going. The $1,000 genome arrived right on schedule, and today sequencing has pushed toward the $100 to $200 range. I even joked in that talk that you’d soon buy a sequencing machine at Radio Shack. That was obviously a gag, but the underlying point was serious: when a cost curve falls this hard, it changes everything downstream. It did. Cheap sequencing is exactly what made the 2006 personalized-medicine thesis economically possible. This is the cleanest hit on the board.