The bottom line
Medicine is becoming more individualized as genomics, biomarkers and data make diagnosis, prevention and treatment more specific to the person.
Why it matters
The move away from one-size-fits-all care changes drug development, clinical decision-making and patient participation. Personalized medicine is increasingly a system of prediction and tailoring rather than a single genomic technology.
From the foresight archive
Jim Carroll first published this as Megatrend #12 on 2025-07-11. He revisited it one year later on 2026-08-20, using the retrospective to test the original call against what had happened since.
In that retrospective, Carroll’s own shorthand assessment was: Nailed it — and it’s bigger than gene editing alone. CRISPR is the headline, but the P4 framework — predictive, personalized, preventive, participatory — is now running quietly in the background of a normal doctor’s visit.
This page treats the 2025 article as the original foresight call and the 2026 article as the first evidence checkpoint. Later signals and scorecards can be attached without rewriting the historical record.